There was a chick like that at the lecture I went to tonight. When she asked her third question, I headed for the door.
The most irritated I've ever been, though, was twice at Vanderbilt. Once, this really annoying guy completely monopolized a wonderful prof who had come to the dorms one night to talk to us. I wanted to ask him how we could make Vandy's atmosphere more intellectual, but couldn't because this jerk kept babbling to the prof about everything he was going to do, how he was perfect and was going to have the most wonderful life because he was so perfect... I really wanted to deck that jerk. The other time was when I went to see a speaker on the recommendation of my history prof. The guy said he'd talk for twenty minutes and then went on for an hour and a half. He was nauseatingly boring. I thought I was going to die, and I had brought a friend, too. And it was a Friday afternoon. And the guy finally finished and asked for questions, and the one person in the room (and possibly the world) who thought this guy was interesting asked a question which basically asked him to continue the talk. Which he did. For another half an hour. My prof had to bring donuts to the history department to earn his colleagues' forgiveness for inviting that dork to speak.